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ON THE NON-EXISTENCE OF SYNERGISM BETWEEN INHALED HYDROGEN CYANIDE AND CARBON MONOXIDE

Lynch, R.D., 1975. ON THE NON-EXISTENCE OF SYNERGISM BETWEEN INHALED HYDROGEN CYANIDE AND CARBON MONOXIDE. Fire Research Notes 1035


ABSTRACT

Rats were exposed either to hydrogen cyanide, or carbon-monoxide, or various mixtures of these two gases to determine the degree of synergism, if any, with respect to the inhalation LCt50s. Within the sensitivity of the measurements, the toxicities of the two gases appear to be purely additive ie no synergism exists.



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